A8V (p.Ala8Val) variant of SOCS1 (O15524)
A8V (p.Ala8Val) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
A8V (p.Ala8Val) variant details
- p.Ala8Val
- Ensembl rs2141125539
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.08
- CADD 23.20
- PolyPhen-2 0.23
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available