A8S (p.Ala8Ser) variant of SOCS1 (O15524)
A8S (p.Ala8Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
A8S (p.Ala8Ser) variant details
- p.Ala8Ser
- cosmic curated COSV10524
- Ensembl rs2141125543
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.02
- CADD 20.30
- PolyPhen-2 0.02
- SIFT 0.46
- Population evidence available
- Structural context available