A47S (p.Ala47Ser) variant of SOCS1 (O15524)
A47S (p.Ala47Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
A47S (p.Ala47Ser) variant details
- p.Ala47Ser
- ExAC rs768681189
- TOPMed rs768681189
- gnomAD rs768681189
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.01
- CADD 10.50
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available