A44T (p.Ala44Thr) variant of SOCS1 (O15524)
A44T (p.Ala44Thr) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A44T (p.Ala44Thr) variant details
- p.Ala44Thr
- gnomAD rs2069585860
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.05
- CADD 12.90
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Middle Eastern population (allele frequency 0.00022)
- Structural context available