A37T (p.Ala37Thr) variant of SOCS1 (O15524)
A37T (p.Ala37Thr) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A37T (p.Ala37Thr) variant details
- p.Ala37Thr
- TOPMed rs2069586201
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.08
- CADD 15.80
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the South Asian population (allele frequency 7.3e-05)
- Structural context available