A35V (p.Ala35Val) variant of SOCS1 (O15524)
A35V (p.Ala35Val) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
A35V (p.Ala35Val) variant details
- p.Ala35Val
- Ensembl rs2141125339
- Missense
- Variant Prioritization Score for Impact Estimate 0.0729
- REVEL 0.01
- CADD 12.40
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the South Asian population (allele frequency 2.4e-05)
- Structural context available