A17S (p.Ala17Ser) variant of SOCS1 (O15524)
A17S (p.Ala17Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A17S (p.Ala17Ser) variant details
- p.Ala17Ser
- cosmic curated COSV59659
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.04
- CADD 17.00
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available