A12S (p.Ala12Ser) variant of SOCS1 (O15524)
A12S (p.Ala12Ser) in SOCS1 (O15524) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A12S (p.Ala12Ser) variant details
- p.Ala12Ser
- cosmic curated COSV10524
- Missense
- Variant Prioritization Score for Impact Estimate 0.378
- REVEL 0.10
- CADD 23.70
- PolyPhen-2 0.77
- SIFT 0.30
- Population evidence available
- Structural context available