P128P (p.Pro128Pro) variant of SNCA (Alpha-synuclein)
P128P (p.Pro128Pro) in SNCA (Alpha-synuclein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
P128P (p.Pro128Pro) variant details
- p.Pro128Pro
- rs1215212302
- gnomAD 4-89702379-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.14
- CADD 8.33
- Population evidence available
- Structural context available
- Deep Mutational Scanning of alpha-Synuclein based on Toxicity in Yeast Treated w: score -0.0131
- Literature evidence available