G132S (p.Gly132Ser) variant of SNCA (Alpha-synuclein)
G132S (p.Gly132Ser) in SNCA (Alpha-synuclein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G132S (p.Gly132Ser) variant details
- p.Gly132Ser
- rs1723915037
- gnomAD 4-89702348-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- CADD 1.17
- Population evidence available
- Structural context available
- Deep Mutational Scanning of alpha-Synuclein based on Toxicity in Yeast Treated w: score -0.0531
- Literature evidence available