Y4H (p.Tyr4His) variant of SMPD1 (Sphingomyelin phosphodiesterase)

Y4H (p.Tyr4His) in SMPD1 (Sphingomyelin phosphodiesterase) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Sphingomyelin/cholesterol lipidosis. The record also includes population frequency data, published literature, and structural context.

Y4H (p.Tyr4His) variant details