P6S (p.Pro6Ser) variant of SMO (Protein smoothened)
P6S (p.Pro6Ser) in SMO (Protein smoothened) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
P6S (p.Pro6Ser) variant details
- p.Pro6Ser
- Ensembl rs2150637729
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.18
- MetaLR 0.21
- MetaSVM -0.81
- CADD 15.50
- PolyPhen-2 0.02
- SIFT 0.68
- Population evidence available
- Structural context available