P26S (p.Pro26Ser) variant of SMO (Protein smoothened)
P26S (p.Pro26Ser) in SMO (Protein smoothened) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P26S (p.Pro26Ser) variant details
- p.Pro26Ser
- Ensembl rs925643027
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.11
- MetaLR 0.23
- MetaSVM -0.96
- CADD 16.10
- PolyPhen-2 0.01
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 1.7e-05)
- Structural context available