G24W (p.Gly24Trp) variant of SMO (Protein smoothened)
G24W (p.Gly24Trp) in SMO (Protein smoothened) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G24W (p.Gly24Trp) variant details
- p.Gly24Trp
- gnomAD rs1486912211
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.24
- MetaLR 0.30
- MetaSVM -0.70
- CADD 27.80
- PolyPhen-2 0.70
- SIFT 0.10
- Population evidence available
- Structural context available