G24R (p.Gly24Arg) variant of SMO (Protein smoothened)
G24R (p.Gly24Arg) in SMO (Protein smoothened) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
G24R (p.Gly24Arg) variant details
- p.Gly24Arg
- gnomAD rs1486912211
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.20
- MetaLR 0.21
- MetaSVM -0.93
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 2.3e-06)
- Structural context available