I91S (p.Ile91Ser) variant of SMC3 (Q9UQE7)
I91S (p.Ile91Ser) in SMC3 (Q9UQE7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
I91S (p.Ile91Ser) variant details
- p.Ile91Ser
- gnomAD rs1860975738
- Missense
- Variant Prioritization Score for Impact Estimate 0.644
- REVEL 0.57
- ESM-1b 1.00
- AlphaMissense 0.64
- CADD 29.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available