F53F (p.Phe53Phe) variant of SMC3 (Q9UQE7)
F53F (p.Phe53Phe) in SMC3 (Q9UQE7) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
F53F (p.Phe53Phe) variant details
- p.Phe53Phe
- rs774284203
- gnomAD 10-110575364-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.164
- CADD 11.70
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available