P15S (p.Pro15Ser) variant of SMARCA2 (P51531)
P15S (p.Pro15Ser) in SMARCA2 (P51531) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
P15S (p.Pro15Ser) variant details
- p.Pro15Ser
- gnomAD 9-2029065-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- REVEL 0.50
- AlphaMissense 0.54
- MetaLR 0.80
- MetaSVM 0.65
- CADD 25.80
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 3.7e-06)
- Structural context available
- Literature evidence available