G24R (p.Gly24Arg) variant of SMARCA2 (P51531)
G24R (p.Gly24Arg) in SMARCA2 (P51531) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
G24R (p.Gly24Arg) variant details
- p.Gly24Arg
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.7
- REVEL 0.65
- AlphaMissense 0.96
- MetaLR 0.78
- MetaSVM 0.69
- CADD 28.80
- PolyPhen-2 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available