M4V (p.Met4Val) variant of SMAD4 (SMAD family member 4)
M4V (p.Met4Val) in SMAD4 (SMAD family member 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes structural context.
M4V (p.Met4Val) variant details
- p.Met4Val
- cosmic curated COSV10886
- Missense
- Variant Prioritization Score for Impact Estimate 0.532
- REVEL 0.51
- ESM-1b 0.00
- AlphaMissense 0.17
- MetaLR 0.93
- MetaSVM 1.07
- CADD 24.40
- Structural context available