T42I (p.Thr42Ile) variant of SLCO1B1 (Q9Y6L6)
T42I (p.Thr42Ile) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T42I (p.Thr42Ile) variant details
- p.Thr42Ile
- 1000Genomes rs576786579
- ExAC rs576786579
- gnomAD rs576786579
- Missense
- Variant Prioritization Score for Impact Estimate 0.228
- REVEL 0.15
- CADD 13.90
- PolyPhen-2 0.01
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available