S63T (p.Ser63Thr) variant of SLCO1B1 (Q9Y6L6)
S63T (p.Ser63Thr) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
S63T (p.Ser63Thr) variant details
- p.Ser63Thr
- gnomAD 12-21172752-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.359
- REVEL 0.27
- MetaLR 0.16
- MetaSVM -0.86
- CADD 22.90
- PolyPhen-2 0.67
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available