S63F (p.Ser63Phe) variant of SLCO1B1 (Q9Y6L6)
S63F (p.Ser63Phe) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
S63F (p.Ser63Phe) variant details
- p.Ser63Phe
- gnomAD 12-21172753-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- REVEL 0.50
- MetaLR 0.44
- MetaSVM 0.18
- CADD 29.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available