S62F (p.Ser62Phe) variant of SLCO1B1 (Q9Y6L6)
S62F (p.Ser62Phe) in SLCO1B1 (Q9Y6L6) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
S62F (p.Ser62Phe) variant details
- p.Ser62Phe
- NCI-TCGA Cosmic COSV5700
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- REVEL 0.33
- CADD 25.60
- PolyPhen-2 0.95
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available