P15T (p.Pro15Thr) variant of SLCO1B1 (Q9Y6L6)
P15T (p.Pro15Thr) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
P15T (p.Pro15Thr) variant details
- p.Pro15Thr
- gnomAD 12-21141617-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0835
- REVEL 0.04
- MetaLR 0.17
- MetaSVM -0.96
- CADD 0.01
- PolyPhen-2 0.01
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available
- Literature evidence available