P15R (p.Pro15Arg) variant of SLCO1B1 (Q9Y6L6)
P15R (p.Pro15Arg) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
P15R (p.Pro15Arg) variant details
- p.Pro15Arg
- gnomAD 12-21141618-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.04
- MetaLR 0.14
- MetaSVM -1.00
- CADD 8.70
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available
- Literature evidence available