N8S (p.Asn8Ser) variant of SLCO1B1 (Q9Y6L6)
N8S (p.Asn8Ser) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
N8S (p.Asn8Ser) variant details
- p.Asn8Ser
- gnomAD 12-21141597-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.08
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -0.98
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available