L43P (p.Leu43Pro) variant of SLCO1B1 (Q9Y6L6)
L43P (p.Leu43Pro) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
L43P (p.Leu43Pro) variant details
- p.Leu43Pro
- ExAC rs770472561
- TOPMed rs770472561
- gnomAD rs770472561
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.35
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available