L31F (p.Leu31Phe) variant of SLCO1B1 (Q9Y6L6)
L31F (p.Leu31Phe) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
L31F (p.Leu31Phe) variant details
- p.Leu31Phe
- gnomAD 12-21172658-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.09
- MetaLR 0.17
- MetaSVM -0.87
- CADD 6.25
- PolyPhen-2 0.62
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available
- Literature evidence available