K28E (p.Lys28Glu) variant of SLCO1B1 (Q9Y6L6)
K28E (p.Lys28Glu) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
K28E (p.Lys28Glu) variant details
- p.Lys28Glu
- gnomAD 12-21141656-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.37
- MetaLR 0.34
- MetaSVM -0.25
- CADD 24.10
- PolyPhen-2 0.65
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available