I61T (p.Ile61Thr) variant of SLCO1B1 (Q9Y6L6)
I61T (p.Ile61Thr) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
I61T (p.Ile61Thr) variant details
- p.Ile61Thr
- gnomAD 12-21172747-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.29
- MetaLR 0.21
- MetaSVM -0.66
- CADD 23.80
- PolyPhen-2 0.86
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available