I55V (p.Ile55Val) variant of SLCO1B1 (Q9Y6L6)
I55V (p.Ile55Val) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
I55V (p.Ile55Val) variant details
- p.Ile55Val
- TOPMed rs915159194
- gnomAD rs915159194
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.25
- CADD 23.80
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available