I55L (p.Ile55Leu) variant of SLCO1B1 (Q9Y6L6)
I55L (p.Ile55Leu) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
I55L (p.Ile55Leu) variant details
- p.Ile55Leu
- TOPMed rs915159194
- gnomAD rs915159194
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.18
- CADD 24.30
- PolyPhen-2 0.81
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available