I52T (p.Ile52Thr) variant of SLCO1B1 (Q9Y6L6)
I52T (p.Ile52Thr) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
I52T (p.Ile52Thr) variant details
- p.Ile52Thr
- Ensembl rs937855856
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.30
- CADD 19.70
- PolyPhen-2 0.36
- SIFT 0.02
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available