I46V (p.Ile46Val) variant of SLCO1B1 (Q9Y6L6)
I46V (p.Ile46Val) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data, published literature, and structural context.
I46V (p.Ile46Val) variant details
- p.Ile46Val
- gnomAD 12-21172701-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0746
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.05
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available
- Literature evidence available