F59L (p.Phe59Leu) variant of SLCO1B1 (Q9Y6L6)
F59L (p.Phe59Leu) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
F59L (p.Phe59Leu) variant details
- p.Phe59Leu
- ExAC rs756167965
- gnomAD rs756167965
- Missense
- Variant Prioritization Score for Impact Estimate 0.684
- REVEL 0.70
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available