A11T (p.Ala11Thr) variant of SLCO1B1 (Q9Y6L6)
A11T (p.Ala11Thr) in SLCO1B1 (Q9Y6L6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
A11T (p.Ala11Thr) variant details
- p.Ala11Thr
- gnomAD 12-21141605-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0638
- REVEL 0.01
- MetaLR 0.05
- MetaSVM -1.01
- CADD 0.24
- PolyPhen-2 0.00
- SIFT 0.90
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available