S75Y (p.Ser75Tyr) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
S75Y (p.Ser75Tyr) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
S75Y (p.Ser75Tyr) variant details
- p.Ser75Tyr
- gnomAD rs1228802510
- Missense
- Variant Prioritization Score for Impact Estimate 0.462
- REVEL 0.24
- CADD 26.50
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.1e-05)
- Structural context available