R134P (p.Arg134Pro) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
R134P (p.Arg134Pro) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R134P (p.Arg134Pro) variant details
- p.Arg134Pro
- TOPMed rs1274645242
- gnomAD rs1274645242
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.20
- CADD 25.70
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available