L74M (p.Leu74Met) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
L74M (p.Leu74Met) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
L74M (p.Leu74Met) variant details
- p.Leu74Met
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.28
- CADD 22.70
- PolyPhen-2 0.91
- SIFT 0.36
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available