L170I (p.Leu170Ile) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
L170I (p.Leu170Ile) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L170I (p.Leu170Ile) variant details
- p.Leu170Ile
- ExAC rs761519337
- gnomAD rs761519337
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.04
- CADD 12.80
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available