L170F (p.Leu170Phe) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
L170F (p.Leu170Phe) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
L170F (p.Leu170Phe) variant details
- p.Leu170Phe
- ExAC rs761519337
- gnomAD rs761519337
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.08
- CADD 15.80
- PolyPhen-2 0.17
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available