L167F (p.Leu167Phe) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
L167F (p.Leu167Phe) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
L167F (p.Leu167Phe) variant details
- p.Leu167Phe
- TOPMed rs1045149774
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.12
- CADD 22.20
- PolyPhen-2 0.58
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available