K77M (p.Lys77Met) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
K77M (p.Lys77Met) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
K77M (p.Lys77Met) variant details
- p.Lys77Met
- TOPMed rs1035048787
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.13
- CADD 27.60
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.7e-05)
- Structural context available