G21W (p.Gly21Trp) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
G21W (p.Gly21Trp) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G21W (p.Gly21Trp) variant details
- p.Gly21Trp
- TOPMed rs1733971078
- gnomAD rs1733971078
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.07
- CADD 21.30
- PolyPhen-2 0.47
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available