G141E (p.Gly141Glu) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
G141E (p.Gly141Glu) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
G141E (p.Gly141Glu) variant details
- p.Gly141Glu
- ExAC rs767647127
- gnomAD rs767647127
- Missense
- Variant Prioritization Score for Impact Estimate 0.715
- REVEL 0.70
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available