A59S (p.Ala59Ser) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
A59S (p.Ala59Ser) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A59S (p.Ala59Ser) variant details
- p.Ala59Ser
- ExAC rs777362477
- gnomAD rs777362477
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.16
- CADD 23.00
- PolyPhen-2 0.09
- SIFT 0.02
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available