A35V (p.Ala35Val) variant of SLC9A3 (Sodium/hydrogen exchanger 3)
A35V (p.Ala35Val) in SLC9A3 (Sodium/hydrogen exchanger 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
A35V (p.Ala35Val) variant details
- p.Ala35Val
- cosmic curated COSV10960
- gnomAD rs1274127342
- Missense
- Variant Prioritization Score for Impact Estimate 0.0849
- REVEL 0.04
- CADD 11.80
- PolyPhen-2 0.01
- SIFT 0.15
- Most common in the Middle Eastern population (allele frequency 0.00019)
- Structural context available