Y2* (p.Tyr2Ter) variant of SLC8A1 (Sodium/calcium exchanger 1)

Name: SLC8A1 Y2* (p.Tyr2Ter) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

Y2* (p.Tyr2Ter) in SLC8A1 (Sodium/calcium exchanger 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.

Y2* (p.Tyr2Ter) variant details

p.Tyr2Ter
ExAC rs768751346
TOPMed rs768751346
gnomAD rs768751346
Stop Gained
Variant Prioritization Score for Impact Estimate 0.66
CADD 34.00
Most common in the Non-Finnish European population (allele frequency 1.5e-05)
Structural context available