P66T (p.Pro66Thr) variant of SLC8A1 (Sodium/calcium exchanger 1)
P66T (p.Pro66Thr) in SLC8A1 (Sodium/calcium exchanger 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
P66T (p.Pro66Thr) variant details
- p.Pro66Thr
- TOPMed rs1690502060
- Missense
- Variant Prioritization Score for Impact Estimate 0.745
- REVEL 0.72
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available